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B379

Dopamine is a so-called neurotransmitter.

10 Arbeidsdager

Spesifikasjoner

Breeds

Gene

Organ

specimen

Fjær, EDTA blod, heparinblod

Mode of Inheritance

Chromosome

Also known as

Year Published

Generell informasjon

Dopamine is a so-called neurotransmitter. Many important physiological functions are mediated by dopamine and its receptors. The dopamine receptor type 4 (DRD4) gene has been scientifically proven to influence the racing performance of pigeons, making it a useful performance marker.

There are two point mutations in the gene: DRD4-Bst4CI (also known as DRD4-1 or DRD4a) and DRD4-MnlI (also known as DRD4-2 or DRD4b).
In this test the presence of the DRD4-MnlI mutation is analysed. This mutation appears to influence character and perseverance, leading to improved performance in long-distance races in heterozygous individuals. The other mutation is available as a separate test.

Kliniske egenskaper

When only the DRD4-MnlI variant is heterozygous, there is a significant positive effect on long-distance performance. However, when both mutations are heterozygous, a combination referred to as double heterozygotes (CTCT individuals), these individuals are often among the best-performing pigeons in extremely long-distance flights.

Tilleggsinformasjon

Referanser

Pubmed ID: 26202371

Omia ID:

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