Krøllete pels med eller uten hypotrikose (SP6- og KRT25-ralert) – Hest

A curly coat in horses, known particularly as the distinctive trait of the American Bashkir Curly Horse, is caused by a complex interaction between two separate genes, KRT25 (this test; P306) and SP6 (DNA test P330). These same genes can also cause hypotrichosis: a loss of tail and mane hair.

A horse with a genotype with GG and CC (GC/GC) is entirely unaffected, and will develop a straight coat with normal thickness. A genotype of GC/GT or GT/GT causes a curly coat. A genotype of GC/AT or GC/AC causes curly coat and incomplete hypotrichosis (scanty tail). Finally, a genotype of AC/AC causes a curly coat with complete hypotrichosis (string tail).