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H986

Haemophilia B, also called Factor IX Deficiency or Christmas Disease, is a blood disorder that impairs clotting, which can lead to uncontrolled bleeding.

10 Arbeidsdager

Spesifikasjoner

Breeds

Gene

Organ

specimen

Swab, Blood EDTA, Blood Heparin, Semen, Tissue
Mode of Inheritance

Chromosome

Also known as

Year Published

Generell informasjon

Haemophilia B, also called Factor IX Deficiency or Christmas Disease, is a blood disorder that impairs clotting, which can lead to uncontrolled bleeding. Haemophilia B is caused by an X-linked recessive mutation to the gene F9. There are many known variants of Haemophilia B, each specific to a particular dog breed. This variant occurs in the Cairn Terrier.

Kliniske egenskaper

Affected dogs are prone to uncontrolled bleeding after injury or surgery, and may develop spontaneous bleeding. Blood analysis will confirm a lack of Factor IX activity and prolonged clotting times.

Tilleggsinformasjon

Referanser

Pubmed ID: 2481310

Omia ID: 438

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