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Macular Corneal dystrophy (MCD) is an eye condition in Labrador Retrievers that causes the corneas to gradually become cloudy, leading to worsening vision.
10 Arbeidsdager
Spesifikasjoner
| Breeds | |
|---|---|
| Gene | |
| Organ | |
| specimen | Svaber, EDTA blod, heparinblod, sæd, vev |
| Mode of Inheritance | |
| Chromosome | |
| Also known as | |
| Year Published |
Generell informasjon
Macular Corneal dystrophy (MCD) is an eye condition in Labrador Retrievers that causes the corneas to gradually become cloudy, leading to worsening vision. It is most likely caused by a recessive mutation in a comparative candidate gene (CHST6), which is also called LOC489707.
Kliniske egenskaper
Onset of MCD is generally between 4.5 and 6 years of age. The cornea becomes gradually cloudy, and develops multiple off-white to yellow-brown opaque spots of varying sizes. Affected dogs may show signs of impaired vision, though complete blindness is generally uncommon.
Tilleggsinformasjon
Referanser
Pubmed ID: 26585178
Omia ID: 2071