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H877

Haemophilia A, also called Factor VIII Deficiency, is the most common bleeding disorder in dogs.

10 Arbeidsdager

Spesifikasjoner

Breeds

Gene

Organ

specimen

Swab, Blood EDTA, Blood Heparin, Semen, Tissue

Mode of Inheritance

Chromosome

Also known as

Year Published

Generell informasjon

Haemophilia A, also called Factor VIII Deficiency, is the most common bleeding disorder in dogs. Caused by an X-linked recessive mutation to the gene F8, the disease strongly impairs the blood’s ability to clot, which can lead to severe symptoms such as spontaneous internal bleeding, or uncontrolled bleeding after injury or surgery.

The specific variant of the disease analysed in this test is found in the Boxer. Related variants are also found in the Irish Setter and Miniature Schnauzer, German Shepherd, Old English Sheepdog, and the Rhodesian Ridgeback.

Kliniske egenskaper

Common clinical signs in dogs include bleeding from the mouth, subcutaneous and intramuscular haematomas and lameness.

Tilleggsinformasjon

Referanser

Pubmed ID: 25040606

Omia ID: 437

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