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The P2RY12 receptor platelet disorder in the Greater Swiss Mountain Dog is a hereditary disease that leaves affected dogs at risk of severe bleeding under surgery or if injured.
10 Arbeidsdager
Spesifikasjoner
| Breeds | |
|---|---|
| Gene | |
| Organ | |
| specimen | Svaber, EDTA blod, heparinblod, sæd, vev |
| Mode of Inheritance | |
| Chromosome | |
| Year Published |
Generell informasjon
The P2RY12 receptor platelet disorder in the Greater Swiss Mountain Dog is a hereditary disease that leaves affected dogs at risk of severe bleeding under surgery or if injured. It is caused by a recessive mutation to the P2RY12 gene, and is described as fairly widespread in the breed.
Kliniske egenskaper
Affiserte hunder virker stort sett normale. Bortsett fra hvis de opplever traumer, gjennomgår kirurgi eller får behandling med blodplatehemmere da dette kan føre til potensielt livstruende blødning.
Tilleggsinformasjon
Referanser
Pubmed ID: 21554368
Omia ID: 1564