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Upper Airway Syndrome (NTUAS) is a breathing disorder found in dogs.
10 Arbeidsdager
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Spesifikasjoner
| Breeds | |
|---|---|
| Gene | |
| Chromosome | 13 |
| Mutation | c.2786G>A |
| Mode of Inheritance | Ukjent |
| Organ | |
| Specimen | Svaber, EDTA blod, heparinblod, sæd, vev |
| Also known as | UAS |
Generell informasjon
Upper Airway Syndrome (NTUAS) is a breathing disorder found in dogs. The disorder is linked to a mutation to the gene ADAMTS3. The mutation has been found in, amongst others, Norwich Terrier, French Bulldog and Staffordshire Bull Terrier.
NTUAS has an symptoms overlap with Brachycephalic Obstructive Airway Syndrome (BOAS), a disorder that causes breathing difficulties in brachycephalic dogs.
The main issues in affected dogs include a slightly elongated soft palate, extra tissue in the throat, and structural changes in the larynx. These abnormalities, caused by the ADAMTS3 mutation, can lead to breathing difficulties of varying severity. Further research is needed to fully understand the range of symptoms.
Kliniske egenskaper
Berørte hunder kan oppleve pustevansker, ofte ledsaget av stridor (tungpustethet eller fnyselyder). Andre mulige symptomer inkluderer forstørrede eller hovne mandler og delvis larynxkollaps. Diagnosen kan være utfordrende uten en laryngoskopisk undersøkelse.
Tilleggsinformasjon
Referanser
Pubmed ID: 31095560
Year published: 2019
Omia ID: 1893
Omia variant ID: 1084