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Hoof wall separation disease (HWSD) is a genetic defect in horses that causes the hoof wall to crack, chip, and break easily, while the coronary band appears normal.
10 Arbeidsdager
Spesifikasjoner
| Breeds | Connemara ponni, Gypsy Vanner, Gypsy vanner (tinker), Tinker |
|---|---|
| Gene | |
| Organ | |
| specimen | Svaber, EDTA blod, heparinblod, sæd, vev |
| Mode of Inheritance | |
| Chromosome | |
| Also known as | |
| Year Published |
Generell informasjon
Hoof wall separation disease (HWSD) is a genetic defect in horses that causes the hoof wall to crack, chip, and break easily, while the coronary band appears normal. Symptoms typically begin in young horses, and in severe cases, the horse may bear weight entirely on the sole of the foot. This abnormal weight-bearing can result in severe pain and lameness. The defect is caused by an autosomal recessive mutation in the serpin peptidase inhibitor, clade B (ovalbumin), member 11 gene (SERPINB11).
HWSD appears to occur in the Connemara Pony, Gypsy Vanner, Tinker and Irish Cob.
Kliniske egenskaper
Hovveggseparasjonssykdom (HWSD) manifesterer seg klinisk som separasjon av dorsalhovveggen langs den vektbærende overflaten av hoven i løpet av det første år av livet.
Tilleggsinformasjon
Referanser
Pubmed ID: 25875171
Omia ID: 1897